Title:A Systematic Study on the Impact of Blueberry Supplementation on Metabolic Syndrome Components
Volume: 21
Issue: 3
Author(s): Shahnaz Yousefizadeh, Tahereh Farkhondeh, Effat Alemzadeh*Saeed Samarghandian*
Affiliation:
- Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
- Healthy Ageing Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran
Keywords:
Blueberries, metabolic syndrome, obesity, diabetes, dyslipidemia, hypertension.
Abstract:
Background: Metabolic syndrome, which is characterized by a constellation of well--
known risk factors, including obesity, hyperlipidemia, insulin resistance, and hypertension, is associated
with an elevated risk of developing diabetes and cardiovascular disease. Given the lifestyle
change, the prevalence of metabolic syndrome has been growing worldwide in recent years. Accordingly,
the pivotal role of diet in the progression of metabolic syndrome as a lifestyle modification
is taken into account.
Aims: This systematic review aimed to explore the association of blueberry consumption with
ameliorating metabolic syndrome.
Methods: We conducted this systematic review under PRISMA (Preferred Reporting Items for
Systematic Reviews and Meta-Analyses) guidelines and performed a systematic literature search
in several databases, including Web of Science, Scopus, PubMed, and Google Scholar.
Results: Six clinical trial studies indicated that blueberries could not change components of
metabolic syndrome, especially blood glucose. However, most of the animal studies indicated the
protective effects of blueberries on these components.
Conclusion: There are evidence suggesting that blueberry may effectively impact metabolic syndrome,
whereas some disputed findings have shown that there is no alteration of metabolic syndrome
components. Further clinical trials are needed to be conducted to investigate the potential
impact of blueberries on metabolic syndrome and address this question.
