Title:Lipid Nanoparticles and Active Natural Compounds: A Perfect Combination for Pharmaceutical Applications
Volume: 26
Issue: 24
关键词:
固体脂质纳米颗粒,纳米结构脂质载体,活性天然化合物,药物递送,稳定性,载体系统
摘要: Phytochemicals represent an important class of bioactive compounds characterized
by significant health benefits. Notwithstanding these important features, their potential therapeutic
properties suffer from poor water solubility and membrane permeability limiting their
approach to nutraceutical and pharmaceutical applications. Lipid nanoparticles are well
known carrier systems endowed with high biodegradation and an extraordinary biocompatible
chemical nature, successfully used as platform for advanced delivery of many active compounds,
including the oral, topical and systemic routes. This article is aimed at reviewing the
last ten years of studies about the application of lipid nanoparticles in active natural compounds
reporting examples and advantages of these colloidal carrier systems.