Title:MoABank: An Integrated Database for Drug Mode of Action Knowledge
Volume: 14
Issue: 5
Author(s): Yu-di Liao and Zhen-ran Jiang*
Affiliation:
- Department of Computer Science and Technology, East China Normal University, Shanghai, 200062,China
Keywords:
Information integration, MoA, database, drug molecular, cheminformatics, bioactivity data.
Abstract:
Background: With the declining trend of new drugs yield each year, more
comprehensive knowledge of drug MoAs can help identify new applications of available drugs and
discovery novel mechanism of drug action.
Objective: Therefore, construction of a specialized drug mode of action (MoA) database is of
paramount importance for new drug research & development.
Methods: This paper introduces an integrated database for drug mode of action knowledge
(MoABank).
Results: This database can provide the knowledge about drug MoAs, targets, pathways, side
effects and other drug-related information for researchers.
Conclusion: We believe MoABank can make it more convenient for users to obtain the drug MoA
information in the future.