[1]
Rong, C.; Feng, Y.; Ye, Z. Notch is a critical regulator in cervical cancer by regulating Numb splicing. Oncol. Lett., 2017, 13, 2465-2470.
[2]
Lan, K.; Zhao, Y.; Fan, Y.; Ma, B.; Yang, S.; Liu, Q.; Linghu, H.; Wang, H. Sulfiredoxin May Promote Cervical Cancer Metastasis via Wnt/β-Catenin Signaling Pathway. Int. J. Mol. Sci., 2017, 18, 917.
[3]
Smith, R.A.; Andrews, K.S.; Brooks, D.; Fedewa, S.A.; Manassaram-Baptiste, D.; Saslow, D.; Brawley, O.W.; Wender, R.C. Cancer screening in the United States, 2017: A review of current American Cancer Society guidelines and current issues in cancer screening. CA Cancer J. Clin., 2017, 67, 100-121.
[4]
Wang, W.; Li, Y.; Liu, N.; Gao, Y.; Li, L. MiR-23b controls ALDH1A1 expression in cervical cancer stem cells. BMC Cancer, 2017, 17, 292. a
[5]
Gu, J.; Hao, C.; Yan, X.; Xuan, S. Applied analysis of ultrasound-guided ilioinguinal and iliohypogastric nerve blocks in the radical surgery of aged cervical cancer. Oncol. Lett., 2017, 13, 1637-1640.
[6]
Zhang, M.; Zhang, H.; Yu, Y.; Huang, H.; Li, G.; Xu, C. Synergistic effects of a novel lipid-soluble extract from Pinelliapedatisecta Schott and cisplatin on human cervical carcinoma cell lines through the regulation of DNA damage response signaling pathway. Oncol. Lett., 2017, 13, 2121-2128.
[7]
Mizuno, T. Medicinal effects and utilization of Cordyceps (Fr.) Link (Ascomycetes) and Isaria Fr. (Mitosporic fungi) Chinese caterpillar fungi, “Tohukaso. Int. J. Med. Mushrooms, 1999, 1, 251-256.
[8]
Khan, M.A.; Tania, M.; Zhang, D.; Chen, H. Cordyceps Mushroom: A Potent Anticancer Nutraceutical. The Open Nutr. J., 2010, 3, 179-183.
[9]
Yoshikawa, N.; Nakamura, K.; Yamaguchi, Y.; Kagota, S.; Shinozuka, K.; Kunitomo, M. Antitumour activity of cordycepin in mice. Clin. Exp. Pharmacol. Physiol., 2004, 31, 51-53.
[10]
Kim, H.G.; Shrestha, B.; Lim, S.Y.; Yoon, D.H.; Chang, W.C.; Shin, D.J.; Han, S.K.; Park, S.M.; Park, J.H.; Park, H.I.; Sung, J.M.; Jang, Y.; Chung, N.; Hwang, K.C.; Kim, T.W. Cordycepin inhibits lipopolysaccharide-induced inflammation by the suppression of NF-kappaB through Akt and p38 inhibition in RAW 264.7 macrophage cells. Eur. J. Pharmacol., 2006, 545, 192-199.
[11]
Wu, W.C.; Hsiao, J.R.; Lian, Y.Y.; Lin, C.Y.; Huang, B.M. The apoptotic effect of cordycepin on human OEC-M1 oral cancer cell line. Cancer Chemother. Pharmacol., 2007, 60, 103-111.
[12]
Tuli, H.S.; Sharma, A.K.; Sandhu, S.S.; Kashyap, D. Cordycepin: a bioactive metabolite with therapeutic potential. Life Sci., 2013, 93, 863-869.
[13]
Nakamura, K.; Shinozuka, K.; Yoshikawa, N. Anticancer and antimetastatic effects of cordycepin, an active component of Cordyceps sinensis. J. Pharmacol. Sci., 2015, 127, 53-56.
[14]
Khan, M.A.; Tania, M.; Wei, C.; Mei, Z.; Fu, S.; Cheng, J.; Xu, J.; Fu, J. Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition. Oncotarget, 2015, 6, 19580-19591.
[15]
Khan, M.A.; Chen, H.C.; Wan, X.X.; Tania, M.; Xu, A.H.; Chen, F.Z.; Zhang, D.Z. Regulatory effects of resveratrol on antioxidant enzymes: a mechanism of growth inhibition and apoptosis induction in cancer cells. Mol. Cells, 2013, 35, 219-225.
[16]
Frisch, M.J.; Trucks, G.W.; Schlegel, H.B.; et al. Gaussian 09,
Revision A.02. Gaussian Inc Wallingford CT 34:Wallingford CT.
2009. doi: 10.1159/000348293
[17]
Trott, O.; Olson, A.J. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J. Comput. Chem., 2010, 31, 455-461.
[19]
Dassault Systèmes, B.I.O.V.I.A. Discovery Studio Modeling Environment. Release 4.1; San Diego: Dassault Systèmes, 2015.
[20]
Maier, J.A.; Martinez, C.; Kasavajhala, K.; Wickstrom, L.; Hauser, K.E.; Simmerling, C. ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB. J. Chem. Theory Comput., 2015, 11, 3696-3713.
[21]
Krieger, F.; Fierz, B.; Bieri, O.; Drewello, M.; Kiefhaber, T. Dynamics of unfolded polypeptide chains as model for the earliest steps in protein folding. J. Mol. Biol., 2003, 332, 265-274.
[22]
Krieger, E.; Darden, T.; Nabuurs, S.B.; Finkelstein, A.; Vriend, G. Making optimal use of empirical energy functions: force-field parameterization in crystal space. Proteins, 2004, 57, 678-683.
[23]
Tom, D.; Darrin, Y.; Lee, P. Particle mesh Ewald: An Nṡlog(N) method for Ewald sums in large systems. J. Chem. Phys., 1993, 98, 10089-10092.
[24]
Chen, Y.Y.; Chou, P.Y.; Chien, Y.C.; Wu, C.H.; Wu, T.S.; Sheu, M.J. Ethanol extracts of fruiting bodies of Antrodia cinnamomea exhibit anti-migration action in human adenocarcinoma CL1-0 cells through the MAPK and PI3K/AKT signaling pathways. Phytomedicine, 2012, 19, 768-778.
[25]
Nakamura, K.; Konoha, K.; Yoshikawa, N.; Yamaguchi, Y.; Kagota, S.; Shinozuka, K.; Kunitomo, M. Effect of cordycepin (3′-deoxyadenosine) on hematogenic lung metastatic model mice. In Vivo, 2005, 19, 137-141.
[26]
Sato, A.; Yoshikawa, N.; Kubo, E.; Kakuda, M.; Nishiuchi, A.; Kimoto, Y.; Takahashi, Y.; Kagota, S.; Shinozuka, K.; Nakamura, K. Inhibitory effect of cordycepin on experimental hepatic metastasis of B16-F0 mouse melanoma cells. In Vivo, 2013, 27, 729-732.
[27]
Yoshikawa, N.; Kunitomo, M.; Kagota, S.; Shinozuka, K.; Nakamura, K. Inhibitory effect of cordycepin on hematogenic metastasis of B16-F1 mouse melanoma cells accelerated by adenosine-5′-diphosphate. Anticancer Res., 2009, 29, 3857-3860.
[28]
Zhang, P.; Huang, C.; Fu, C.; Tian, Y.; Hu, Y.; Wang, B.; Strasner, A.; Song, Y.; Song, E. Cordycepin (3′-deoxyadenosine) suppressed HMGA2, Twist1 and ZEB1-dependent melanoma invasion and metastasis by targeting miR-33b. Oncotarget, 2015, 6, 9834-9853.
[29]
Chaicharoenaudomrung, N.; Jaroonwitchawan, T.; Noisa, P. Cordycepin induces apoptotic cell death of human brain cancer through the modulation of autophagy. Toxicol. In Vitro, 2017, 46, 113-121.
[30]
Shao, L.W.; Huang, L.H.; Yan, S.; Jin, J.D.; Ren, S.Y. Cordycepin induces apoptosis in human liver cancer HepG2 cells through extrinsic and intrinsic signaling pathways. Oncol. Lett., 2016, 12, 995-1000.
[31]
Hwang, J.H.; Park, S.J.; Ko, W.G.; Kang, S.M.; Lee, D.B.; Bang, J.; Park, B.J.; Wee, C.B.; Kim, D.J.; Jang, I.S.; Ko, J.H. Cordycepin induces human lung cancer cell apoptosis by inhibiting nitric oxide mediated ERK/Slug signaling pathway. Am. J. Cancer Res., 2017a, 7, 417-432.
[32]
Joo, J.C.; Hwang, J.H.; Jo, E.; Kim, Y.R.; Kim, D.J.; Lee, K.B.; Park, S.J.; Jang, I.S. Cordycepin induces apoptosis by caveolin-1-mediated JNK regulation of Foxo3a in human lung adenocarcinoma. Oncotarget, 2017, 8, 12211-12224.
[33]
Wang, Z.; Wu, X.; Liang, Y.N.; Wang, L.; Song, Z.X.; Liu, J.L.; Tang, Z.S. Cordycepin Induces Apoptosis and Inhibits Proliferation of Human Lung Cancer Cell Line H1975 via Inhibiting the Phosphorylation of EGFR. Molecules, 2016, 21, E1267.
[34]
Yu, X.; Ling, J.; Liu, X.; Guo, S.; Lin, Y.; Liu, X.; Su, L. Cordycepin induces autophagy-mediated c-FLIPL degradation and leads to apoptosis in human non-small cell lung cancer cells. Oncotarget, 2017, 8, 6691-6699.
[35]
Hwang, I.H.; Oh, S.Y.; Jang, H.J.; Jo, E.; Joo, J.C.; Lee, K.B.; Yoo, H.S.; Lee, M.Y.; Park, S.J.; Jang, I.S. Cordycepin promotes apoptosis in renal carcinoma cells by activating the MKK7-JNK signaling pathway through inhibition of c-FLIPL expression. PLoS One, 2017b, 12, e0186489.
[36]
Cao, H.L.; Liu, Z.J.; Chang, Z. Cordycepin induces apoptosis in human bladder cancer cells via activation of A3 adenosine receptors. Tumour Biol., 2017, 39, 1010428317706915.
[37]
Wang, C.W.; Hsu, W.H.; Tai, C.J. Antimetastatic effects of cordycepin mediated by the inhibition of mitochondrial activity and estrogen-related receptor α in human ovarian carcinoma cells. Oncotarget, 2017b, 8, 3049-3058.
[38]
Nasser, M.I.; Masood, M.; Wei, W.; Li, X.; Zhou, Y.; Liu, B.; Li, J.; Li, X. Cordycepin induces apoptosis in SGC-7901 cells through mitochondrial extrinsic phosphorylation of PI3K/Akt by generating ROS. Int. J. Oncol., 2017, 50, 911-919.
[39]
van den Heuvel, S.; Harlow, E. Distinct roles for cyclin-dependent kinases in cell cycle control. Science, 1993, 262, 2050-2054.
[40]
Hu, B. Mitra, J.; van den Heuvel, S.; Enders, G.H. S and G2 phase roles for Cdk-2 revealed by inducible expression of a dominant-negative mutant in human cells. Mol. Cell. Biol., 2001, 21, 2755-2766.
[41]
Liao, Y.; Ling, J.; Zhang, G.; Liu, F.; Tao, S.; Han, Z.; Chen, S.; Chen, Z.; Le, H. Cordycepin induces cell cycle arrest and apoptosis by inducing DNA damage and up-regulation of p53 in Leukemia cells. Cell Cycle, 2015, 14, 761-771.
[42]
Seong da, B.; Hong, S.; Muthusami, S.; Kim, W.D.; Yu, J.R.; Park, W.Y. Cordycepin increases radiosensitivity in cervical cancer cells by overriding or prolonging radiation-induced G2/M arrest. Eur. J. Pharmacol., 2016, 771, 77-83.
[43]
Siev, M.; Weinberg, R.; Penman, S. The selective interruption of nucleolar RNA synthesis in HeLa cells by cordycepin. J. Cell Biol., 1969, 41, 510-520.
[44]
Bissantz, C.; Kuhn, B.; Stahl, M. A medicinal chemist’s guide to molecular interactions. J. Med. Chem., 2010, 53, 5061-5084.
[45]
Hunter, C.A. Quantifying intermolecular interactions: guidelines for the molecular recognition toolbox. Angew. Chem. Int. Ed. Engl., 2004, 43, 5310-5324.
