Title:Chemistry and Biology of Secondary Metabolites from Aspergillus Genus
Volume: 8
Issue: 4
Author(s): Xiaolei Zhang, Zhi Li and Jiangtao Gao*
Affiliation:
- College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou,China
Keywords:
Aspergillus, secondary metabolites, structure, biological activity, ubiquitous fungi, genome sequencing.
Abstract: Aspergillus is a genus of ubiquitous fungi that are therapeutically important because the
genus produces a wide range of structurally diverse secondary metabolites that are of highly considerable
interest to both scientific research community and pharmaceutical industry. Genome sequencing
results have indicated that chemical diversity of secondary metabolites is much larger in each
species than previously thought. This review summarizes a total of 315 new secondary metabolites
of Aspergillus reported from 2015 to 2017 and demonstrates the therapeutical potential of this genus
by introducing their unique chemical structures and excellent bioactivities from this genus.