Title:Cyclic Dipeptides: Secondary Metabolites Isolated from Different Microorganisms with Diverse Biological Activities
Volume: 24
Issue: 25
Author(s): Aurelio Ortiz and Estibaliz Sansinenea*
Affiliation:
- Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, C.P. 72570, Puebla, Pue,Mexico
Keywords:
Cyclic dipeptides, Secondary metabolites, Biological activities, diketopiperazines, cyclo(L-pro), natural
compounds.
Abstract: Cyclic dipeptides are the simplest peptide derivatives commonly found in nature.
These chiral molecules are easily synthesized from readily available α-amino acids using a
simple methodology. They are privileged structures with the ability to bind to a wide range of
receptors and have a broad variety of biological and pharmacological activities. We will give
a brief overview of their status giving and interesting reference list about the last works.