Title:Recent Advancemnts in Biodegradable Ocular Implants
Volume: 15
Issue: 2
Author(s): Swati Mittal and Oshin Miranda*
Affiliation:
- Department of Pharmacology, University of Minnesota (Medical School Twin cities), Minnesota, 55455,United States
Keywords:
Biodegradable polymers, biodegradable implants, advancements, pharmaceutical technology, ocular implants,
bioavailability.
Abstract: The perpetuation of healthy vision is paramount in an individual. It has been observed that
various drug delivery systems have been fabricated to develop vision quality in individuals. Systemic
ocular drug therapies have limited efficacy due to poor bioavailability, systemic and toxic side effects
and low patient compliance. Various drug systems which follow the ocular route of administration are
manufactured to achieve optimized bioavailability along with better patient compliance. Ocular implant
is one such example. It is divided into biodegradable and non-biodegradable drug delivery systems
wherein the former is more beneficial. This review aims to demonstrate the current momentum in the formulation
and optimization of various biodegradable ocular drug delivery systems and its characteristics.