Title:A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica)
Volume: 3
Issue: 3
Author(s): Mona Semalty, Lokesh Adhikari, Divya Semwal, Anita Chauhan, Akash Mishra, Rupali Kotiyal and Ajay Semalty*
Affiliation:
- Department of Pharmaceutical Sciences, H.N.B. Garhwal (Central) University Srinagar (Garhwal)-246174, Uttarakhand,India
Keywords:
Alopecia, analgesic, anti-arthritic, antihypertensive, anti-inflammatory, 5 alpha reductase inhibitor,
BPH, herbal remedy, nettle, urtica.
Abstract: Background and Objective: Urtica dioica (stinging nettle), a member of the Urticaceae
family, has been used in various traditional systems of medicines since ancient times
especially for joint pain, arthritis and prostate problems. Its roots and leaves contain a wide
variety of bioactive constituents like sterols, fatty acids, lectins terpenes, phenylpropanes,
lignans and coumarins. The leaves and root extract shows various activities like hypoglycemic,
anti-inflammatory, antiproliferative, antioxidant, hypolipemic, antirheumatic, anticarcinogenic
and antiviral activity. It shows its effects through the inhibition of aromatase, 5
α-reductase, cell proliferation and Na+, K+-ATPase inhibition.
Conclusion: The article reviews the phytochemistry and phytopharmacology of the plant.