Title:Advantages of Structure-Based Drug Design Approaches in Neurological Disorders
Volume: 15
Issue: 8
Author(s): Murali Aarthy, Umesh Panwar, Chandrabose Selvaraj and Sanjeev Kumar Singh*
Affiliation:
- Computer Aided Drug Design and Molecular Modeling Lab, Department of Bioinformatics, Alagappa University, Karaikudi-630004, Tamil Nadu,India
Keywords:
Neurological disorders, Computational Aided drug design, Structure based drug design, Targets, Drug delivery
Abstract: Objective: The purpose of the review is to portray the theoretical concept on neurological
disorders from research data.
Background: The freak changes in chemical response of nerve impulse causes neurological
disorders. The research evidence of the effort done in the older history suggests that the biological drug
targets and their effective feature with responsive drugs could be valuable in promoting the future
development of health statistics structure for improved treatment for curing the nervous disorders.
Methods: In this review, we summarized the most iterative theoretical concept of structure based
drug design approaches in various neurological disorders to unfathomable understanding of reported
information for future drug design and development.
Results: On the premise of reported information we analyzed the model of theoretical drug designing
process for understanding the mechanism and pathology of the neurological diseases which covers
the development of potentially effective inhibitors against the biological drug targets. Finally, it also
suggests the management and implementation of the current treatment in improving the human health
system behaviors.
Conclusion: With the survey of reported information we concluded the development strategies of
diagnosis and treatment against neurological diseases which leads to supportive progress in the drug
discovery.
