Title:Gastric Cancer: Nanoparticles as Tools to Improve Treatment Efficacy
Volume: 22
Issue: 39
Author(s): Ariel R. Guerrero, Felipe Oyarzun-Ampuero, Natalia Hassan, Alejandro H. Corvalan, Andrew F.G. Quest and Marcelo J. Kogan
Affiliation:
Keywords:
Nanoparticles, nanocarriers, gastric cancer, treatment, drug delivery, targeting.
Abstract: In recent years, advances in nanotechnology have raised the specter of developing
effective agents for the treatment of high-impact diseases, like gastric cancer, which remains
one of the major causes of cancer deaths worldwide. This article reviews advances in the
treatment of this pathology using several types of nanoparticles. First, we start with an overview
of gastric cancer, its prevention, detection and the available treatments. Then, we discuss
nanotechnology-based novel strategies using polymeric nanosystems, nanovesicular
systems and inorganic nanoparticles. All of these systems are being evaluated in the perspective
of improving the targeting of anticancer drugs and reducing their negative side
effects.
