Title:Systemic Lupus Erythematosus: Correlation Between Immunodysregulation and Clinical Manifestations
Volume: 12
Issue: 2
Author(s): O. Ismael P. Carneiro and Iva H.O. Brito
Affiliation:
Keywords:
Autoantibodies, clinical manifestations, immunodysregulation, immunoregulation, pathogenesis, systemic lupus
erythematous.
Abstract: Systemic Lupus Erythematosus is considered a prototype of an autoimmune disorder. The
greatly compromise immune system reflects in a global loss of self-tolerance and an array of autoantibodies
which are the hallmark of the disease. Diagnosis and clinical management are a challenge to
physicians owing its complex clinical course. Specific correlation between immunodysregulation and
the clinical manifestations have been studied and we intended in this paper to review recent studies,
highlighting new discoveries in this matter.
