Title:Biological and Chemical Diversity of Coral-Derived Microorganisms
Volume: 22
Issue: 32
Author(s): Xue-Mei Hou, Ru-Fang Xu, Yu-Cheng Gu, Chang-Yun Wang and Chang-Lun Shao
Affiliation:
Keywords:
Alkaloids, antifouling, antimicroorganisms, antitumor, biodiversity, coral-derived microorganisms,
polyketides.
Abstract: Coral-derived microorganisms have been a major focus of many
research efforts on marine ecology in recent decades. Importantly, research on
bioactive compounds from these diverse microorganisms, which include fungi
and bacteria, has experienced an explosive growth during the past five years. This has unveiled the ecological
roles of these microorganisms, which prevent antifouling, inhibit pathogenic bacteria, and deter predators in
ocean ecosystems. Moreover, the structural diversity and pharmacological activity of the compounds produced
by these microorganisms have also been studied extensively, leading not only to an understanding their
roles within ecosystems, but also the potential value of their use in human health. In this review, 258 marine
natural products, including polyketides, terpenoids, meroterpenoids, alkaloids, peptides, shikimates and lipids,
all discovered in the past 24 years, are presented. 146 references are cited.
