Microwave Assisted Synthesis and Antifungal Activity of Some Novel Hydrazones Containing Pyridine Moiety

Title:Microwave Assisted Synthesis and Antifungal Activity of Some Novel Hydrazones Containing Pyridine Moiety

Volume: 13 Issue: 4

Author(s): Li-Jing Min, Yan-Xia Shi, Ming-Yan Yang, Zhi-Wen Zhai, Jian-Quan Weng, Cheng-Xia Tan, Xing-Hai Liu, Bao-Ju Li and Yong-Gang Zhang

Affiliation:

Keywords: Hydrazone, pyridine, microwave assistant synthesis, antifungal activity.

Abstract: A series of novel hydrazone derivatives containing pyridine moiety were designed and synthesized from 2,3-dichloro-5-(trifluoromethyl)pyridine as starting materials under microwave irradiation, and their structures were characterized by ₁H NMR, MS and elemental analysis. The biological activity of title compounds was determined. The results indicated that some of title compounds exhibited good antifungal activity.

Cite this article as:

Min Li-Jing, Shi Yan-Xia, Yang Ming-Yan, Zhai Zhi-Wen, Weng Jian-Quan, Tan Cheng-Xia, Liu Xing-Hai, Li Bao-Ju and Zhang Yong-Gang, Microwave Assisted Synthesis and Antifungal Activity of Some Novel Hydrazones Containing Pyridine Moiety, Letters in Drug Design & Discovery 2016; 13 (4) . https://dx.doi.org/10.2174/1570180812666151003002140

DOI https://dx.doi.org/10.2174/1570180812666151003002140	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X