Title:Nanomaterial Based Approaches for the Diagnosis and Therapy of Cardiovascular Diseases
Volume: 21
Issue: 30
Author(s): Piyoosh A. Sharma, Rahul Maheshwari, Muktika Tekade and Rakesh Kumar Tekade
Affiliation:
Keywords:
Cardiovascular diseases, nanomaterials, liposomes, gold nanoparticles, magnetic nanoparticles, carbon nanotubes, theranostics.
Abstract: The increasing prevalence and complexity of cardiovascular diseases demand innovative strategies for
diagnostic and therapeutic applications to improve patient care/prognoses. Additionally, various factors constrain
present cardiovascular therapies, including low aqueous drug solubility, early metabolism, short half-life and drug
delivery limitations. The efficient treatment of cardiovascular diseases requires improvement of traditional drug delivery systems. This
can be accomplished by using novel nanomaterial that can incorporate diverse bio-actives along with diagnostic agents in a single carrier,
referred to as theranostics. This review discusses the state of the art in the applications to diagnosis and therapy of innovative, nanomaterial-
based strategies such as lipid based carriers, nanocapsules, magnetic nanoparticles, gold nanoparticles, protein conjugated nanoparticles,
dendrimers and carbon-based nanoformulations with a special emphasis on how they can contribute to improving the management
of cardiovascular disease.
