Title:Nano-Based Anti-Tubercular Drug Delivery and Therapeutic Interventions in Tuberculosis
Volume: 18
Issue: 1
Author(s): Rohit Sharma, Amanpreet Kaur, A. K. Sharma, Neeraj Dilbaghi and Anil K. Sharma
Affiliation:
Keywords:
Nanomedicine, TB, nanocarriers, drugs, drug regimen.
Abstract: Nanotechnology has shown great promise in health care offering numerous possibilities to
significantly improve diagnosis of many dreadful diseases including Tuberculosis (TB). Nanomedicine
has made the current drug regimen more effective against diseases particularly TB with attributes
like sustained release, increased half life, higher drug concentrations at target sites, reduced toxicity
and lesser side effects. However because of the severity of the disease, there is a strong urge to develop
better approaches with some concomitant regimens using nano-particles to diagnose, treat and
manage TB patients. The current review highlights some of the evolving strategies in the field of
nanomedicine particularly drug delivery offering promising alternative for the current TB regimens.
The study also emphasizes upon the need to design more effective nanocarriers which are highly specific,
biocompatible and biodegradable as well.