Title:Nano-constructed Carriers Loaded With Antioxidant: Boon For Cardiovascular System
Volume: 21
Issue: 30
Author(s): Ashay Jain, Prashant Kesharwani, Neeraj Kumar Garg, Atul Jain, Pradip Nirbhavane, Nitin Dwivedi, Sanjeev Banerjee, Arun K. Iyer and Mohd Cairul Iqbal Mohd Amin
Affiliation:
Keywords:
Antioxidants, cardiovascular diseases, liposomes, nanoparticles, nanoemulsions.
Abstract: In the last couple of decades antioxidant agents have entered the health market as an easy and attractive
means of managing diseases. These agents are of enormous interest for an increasingly health-concerned society,
and may be particularly relevant for prophylaxis of a number of diseases i.e. arthritis, cancer, metabolic and cardiovascular
diseases, osteoporosis, cataracts, brain disorders, etc. Antioxidants are also favorable to vascular
healthiness and symbolize useful compounds because they are able to diminish overall cardiovascular risk by acting analogous to first
line therapy or as adjuvants in case of failure or in situations where first line therapy cannot be used. Furthermore, well-designed trials are
indeed needed to improve the therapeutic efficacy and health benefits of antioxidants. Numerous in vivo proof-of-concepts studies are offered
to underline the feasibility of nanostructure system in order to optimizing the delivery of cardiovascular drugs. The present review
highlights the recent approaches for management of cardiovascular disease using different vesicular and particulate carriers, including
liposomes, nanoparticles, and nanoemulsions, with a primary emphasis on those which are expected to enhance the antioxidants level.
