Title:Material Couture for Wound Healing and Regeneration: an Overview
Volume: 21
Issue: 12
Author(s): Indu Pal Kaur, Simarjot Kaur Sandhu, Parneet Kaur Deol, Gaurav Sharma, Monika Yadav and Mandeep Singh
Affiliation:
Keywords:
Polymers, wound dressing, classification, medicated dressings, marketed dressings.
Abstract: Wound healing is a complex regenerative process of great importance in clinical medicine, controlled by temporal
interactions between cells, extracellular matrix components and signalling molecules. Localised delivery of therapeutic active
agents viz. antimicrobials, soothing minerals and/or vitamins and growth factors at the site of injury/trauma/wound are expected
to be more effective and will always manifest milder toxic concerns than those observed upon systemic administration
of these agents. Since ancient times, search is on for suitable materials which may restore or reproduce a favourable and a
natural milieu required for skin regeneration, so as to prevent infections, and make the process fast and less painful. The journey
started with the use of natural materials with a simple function of covering or dressing the wounds to more advanced
materials of present times, which are designed for specific and extraordinary functions. Natural and modified or synthetic
polymers; alone or in combination are commonly used as dressing (couture) materials for wound healing. This article offers a review of
materials that have been used to design and develop wound dressings.
