Title:Review of Procedures Used for the Extraction of Anti-Cancer Compounds from Tropical Plants
Volume: 15
Issue: 3
Author(s): Saurabh Pandey, Paul N. Shaw and Amitha K. Hewavitharana
Affiliation:
Keywords:
Anti-cancer, bio actives, drug discovery, extraction, tropical plants.
Abstract: Tropical plants are important sources of anti-cancer lead molecules. According to the US National Cancer
Institute, out of the 3000 plants identified as active against cancer using in vitro studies, 70% are of tropical origin.
The extraction of bioactive compounds from the plant materials is a fundamental step whose efficiency is critical for
the success of drug discovery efforts. There has been no review published of the extraction procedures of anti-cancer
compounds from tropical plants and hence the following is a critical evaluation of such procedures undertaken prior to
the use of these compounds in cancer cell line studies, during the last five years. It presents a comprehensive analysis
of all approaches taken to extract anti-cancer compounds from various tropical plants. (Databases searched were
PubMed, SciFinder, Web of Knowledge, Scopus, Embase and Google Scholar).
