Title:Universal Nature of Spondyloarthropathy as a Reactive Disease, Reflecting Differential Sensitivities
Volume: 9
Issue: 2
Author(s): Bruce M. Rothschild
Affiliation:
Keywords:
Spondyloarthropathy, rheumatoid arthritis, calcium pyrophosphate deposition disease, gout, primate, bear.
Abstract: Tendency to afflict one part of the skeleton, rather than another, could be referred to as the osseotropism of the
disease. That term would also include which part of the particular bone was affected. That, in addition to characteristics of
erosions, facilitates distinguishing spondyloarthropathy from rheumatoid arthritis, calcium pyrophosphate deposition disease
and gout. Spondyloarthropathy, however, is not limited to humans. Initially recognized in 20% of gorillas and rhesus
macaques, it was subsequently identified in 25% of bears and 35% of rhinoceros. It is truly a pan-mammalian phenomenon,
extending from marsupials and rodents to whales and as ancient as dinosaurs.
