Title:Pre-CKD- Do we Need Another Hero?
Volume: 12
Issue: 4
Author(s): Jolanta Malyszko and Maciej Banach
Affiliation:
Keywords:
Blood pressure, chronic kidney disease, hypertension, prediabetes, prehypertension.
Abstract: Screening is the systematic use of a test for a health problem or risk factor when no recognized signs or symptoms
would indicate the presence of that problem or risk factor. Abnormal glucose metabolism can be documented years
before the onset of overt diabetes. Nowadays, prediabetes can be subdivided into impaired fasting glucose or impaired
glucose tolerance. Substantial number of subjects with either will progress to overt diabetes within years. Prediabetes
bears also the increased risk of cardiovascular complications. Prehypertension is much newer term introduced by the seventh
report of the Joint National Committee (JNC 7) published in 2003 as systolic blood pressure from 120 to 139 mmHg
or diastolic blood pressure from 80 to 89 mmHg in adults (not receiving blood pressure-lowering treatment). Similarly
prehypertension also increased the risk of cardiovascular complications and progression to hypertension. Chronic kidney
disease is also highly prevalent mainly in the elderly. It is associated with important adverse outcomes such as cardiovascular
mortality and morbidity. Factors associated with higher risk of chronic kidney disease include mainly hypertension,
diabetes, obesity and older age. Early detection and diagnosis of chronic kidney disease may prevent the full blown disease
and its end-stage requiring renal replacement therapy. The review focus on the problem of high risk population for
development of diabetes, hypertension and whether time has come to focus also on the conditions predisposing to the
development of chronic kidney disease.
