Title:Pentoxifylline Use in Dermatology
Volume: 11
Issue: 6
Author(s): Seray Kulcu Cakmak, Atil Cakmak, Muzeyyen Gonul, Arzu Kilic and Ulker Gul
Affiliation:
Keywords:
Dermatology, disorder, pentoxifylline, treatment, tumor necrosis factor-α inhibitor, Anti-inflammatory, Venous ulcers, Behcet’s Disease, Recurrent Aphthous Stomatitis, Vasculopathy, Cutaneous Leishmaniasis
Abstract: Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug.
Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour
necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious
in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in
various dermatological disorders.