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Inflammation & Allergy - Drug Targets (Discontinued)

Editor-in-Chief

ISSN (Print): 1871-5281
ISSN (Online): 2212-4055

Pentoxifylline Use in Dermatology

Author(s): Seray Kulcu Cakmak, Atil Cakmak, Muzeyyen Gonul, Arzu Kilic and Ulker Gul

Volume 11, Issue 6, 2012

Page: [422 - 432] Pages: 11

DOI: 10.2174/187152812803590028

Price: $65

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Abstract

Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders.

Keywords: Dermatology, disorder, pentoxifylline, treatment, tumor necrosis factor-α inhibitor, Anti-inflammatory, Venous ulcers, Behcet’s Disease, Recurrent Aphthous Stomatitis, Vasculopathy, Cutaneous Leishmaniasis


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