Title:Effect of Electromagnetic Field on the Polymerization of Microtubules Extracted from Rat Brain
Volume: 6
Issue: 3
Author(s): Mousavi Taghi, Riazi Gholamhosein and Rezayi-zarchi Saeed
Affiliation:
Keywords:
Electromagnetic field, microtubules, polymerization, rat brain.
Abstract: Microtubules (MTs) are ubiquitous eukaryotic proteinaceous filaments showing a hollow cylindrical structure.
MTs are composed of α-β-tubulin heterodimers arranged in linear protofilaments. MTs have a significant electric dipolar
moment along their axes, which makes them capable of being aligned parallel to the applied electromagnetic field direction.
Tubulin heterodimers were purified from rat brains. MTs were obtained by polymerization in vitro. Samples of microtubules
adsorbed under and without electromagnetic fields with 500 Hz frequency. Our results demonstrate the effect
of electromagnetic field with 500 Hz frequency to increase the polymerization of MTs. Some relevant patents are also outlined
in this article.
