Title: Antiviral Activity Of Ribosome Inactivating Proteins In Medicine
Volume: 4
Issue: 5
Author(s): Bijal A. Parikh and Nilgun E. Tumer
Affiliation:
Keywords:
antiviral activity, ribosome inactivating proteins, rrna, rips
Abstract: Pokeweed antiviral protein and several other ribosome inactivating proteins are effective against a broad range of viruses. Recent results have shown that their enzymatic activity is not limited to depurination of the large rRNA, they can depurinate other nucleic acids, including viral RNAs. Antiviral activity of RIPs is summarized here in light of their novel activities and recent developments in the field.