Title:Liposomal Nano-Based Drug Delivery Systems for Breast Cancer Therapy: Recent
Advances and Progresses
Volume: 24
Issue: 12
Author(s): Mostafa Yazdan, Seyed Morteza Naghib*M. R. Mozafari
Affiliation:
- Department of Nanotechnology, School of Advanced Technologies, Iran University of Science and Technology (IUST), Tehran,
1684613114, Iran
Keywords:
Breast cancer, liposomes, anti-cancer agents, drug delivery, targeting, nanotechnology.
Abstract: Breast cancer is a highly prevalent disease on a global scale, with a 30% incidence rate among women
and a 14% mortality rate. Developing countries bear a disproportionate share of the disease burden, while countries
with greater technological advancements exhibit a higher incidence. A mere 7% of women under the age of
40 are diagnosed with breast cancer, and the prevalence of this ailment is significantly diminished among those
aged 35 and younger. Chemotherapy, radiation therapy, and surgical intervention comprise the treatment protocol.
However, the ongoing quest for a definitive cure for breast cancer continues. The propensity for cancer stem
cells to metastasize and resistance to treatment constitute their Achilles' heel. The advancement of drug delivery
techniques that target cancer cells specifically holds significant promise in terms of facilitating timely detection
and effective intervention. Novel approaches to pharmaceutical delivery, including nanostructures and liposomes,
may bring about substantial changes in the way breast cancer is managed. These systems offer a multitude of
advantages, such as heightened bioavailability, enhanced solubility, targeted tumor destruction, and diminished
adverse effects. The application of nano-drug delivery systems to administer anti-breast cancer medications is a
significant subject of research. This article delves into the domain of breast cancer, conventional treatment methods,
the incorporation of nanotechnology into managerial tactics, and strategic approaches aimed at tackling the
disease at its core.