Title:Exploring the Potential Benefits of Bovine Colostrum Supplementation in the Management of Diabetes and its Complications: A Comprehensive Review
Volume: 21
Issue: 2
Author(s): Isha Chawla, Meenakshi Dhanawat, Manu Sharma and Sumeet Gupta*
Affiliation:
- Department of Pharmacology, M. M. College of Pharmacy, M. M. Deemed to be University, Mullana, Ambala, 133207,
India
Keywords:
Colostrum, supplementation therapy, diabetes, renal failure, colostrum, lactoprotein.
Abstract:
Diabetes is a metabolic illness marked by elevated levels of glucose in the bloodstream
due to the inadequate production or use of insulin in the body. Diabetes can result in a
range of consequences, with the most prevalent being cardiovascular disease, renal failure, vision
loss, and limb removal. Natural compounds isolated from different sources, like colostrum, are
the most important compounds for the treatment of diabetes. Colostrum is a form of lactation
produced by mammals in the first days after giving birth to their offspring, having a rich source
of constituents and showing multipharmacological properties.
This review was prepared on the basis of a variety of authoritative search databases, including
Google Scholar, Scopus, and PubMed. In addition, the publications and other online sources
were also included. In the literature search, the terms "colostrum," "diabetes," "uses," "management,"
"constituent," "composition," "alternative sources," "mechanism of action," "preclinical,"
"clinical," "marketed formulations," and "patents" were utilized as keywords and collected from
last two decades.
Colostrum has been utilized as a treatment for a wide variety of illnesses due to its active constituents.
A variety of colostrums are available in the market, like goat colostrum, porcine colostrum,
sheep colostrum, human colostrum and many more. They have the full potential of nutrients
like minerals, vitamins, lactose, essential enzymes, proteins and high concentrations of immunoproteins.
Mostly, the colostrums are used for treating diabetes and its complications. Preclinical
and clinical studies of metabolic syndrome, especially on diabetes and its complications,
were also reported at the National and International levels, which evidently prove that the use of
colostrums in the long term can be beneficial for various ailments associated with diabetes.
In general, the findings of this review indicate that supplementation with colostrum may hold
promise as a novel therapeutic intervention for people who have diabetes and its complications;
however, additional research is required to fully understand its mechanisms of action and determine
the best possible dosage as well as the time period of supplementation.
