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Review Article

铁相关生物标志物在铁疾病诊断和治疗中的应用

卷 31, 期 27, 2024

发表于: 19 February, 2024

页: [4233 - 4248] 页: 16

弟呕挨: 10.2174/0109298673263003231228060800

价格: $65

摘要

背景：缺铁和与铁有关的疾病是世界范围内常见的健康问题，影响着很大一部分人口。这些疾病的诊断和管理在很大程度上依赖于使用各种铁相关的生物标志物，这些生物标志物可以提供有价值的临床信息。 目的：本文综述了最常用的铁相关生物标志物，包括血清铁蛋白、转铁蛋白饱和度、可溶性转铁蛋白受体、锌原卟啉和游离红细胞原卟啉。其他新兴的生物标志物，如铁调素和视黄醇结合蛋白4，也进行了讨论。 结果：铁在各种生理过程中起着至关重要的作用，包括氧运输、能量代谢和DNA合成。本文重点介绍了铁生物标志物的优点和局限性，以及它们在诊断和治疗缺铁及铁相关性贫血中的临床应用。 结论：在筛查和监测项目中使用铁相关的生物标志物可以改善患者的预后并降低医疗成本。

关键词: 铁，缺铁，铁相关疾病，生物标志物，hepcidin，血清铁蛋白。

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