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Review Article

白藜芦醇及其新制剂对肺癌的治疗作用:生物学方面和潜在途径的重点

卷 31, 期 27, 2024

发表于: 31 January, 2024

页: [4340 - 4361] 页: 22

弟呕挨: 10.2174/0109298673266259231229050937

价格: $65

Open Access Journals Promotions 2
摘要

肺癌是全世界死亡和发病的主要原因。由于治疗策略的显著进步，患者的生存和生活质量得到了提高，但仍迫切需要开发更有效的治疗方法。白藜芦醇是一种具有多种生物潜力的天然多酚，已被广泛研究。它通过调节细胞凋亡等关键细胞信号以及microRNA调节等分子途径，在神经退行性疾病、心血管疾病和癌症等多种疾病中显示出治疗潜力。据报道，白藜芦醇在体内和体外均具有抗肺癌的作用。白藜芦醇可以通过调节氧化应激、炎症、细胞凋亡、自噬等多种分子靶点和信号通路以及microRNA的表达来对抗肺癌。此外，最近引入了新的传递系统和类似物来促进白藜芦醇的抗癌作用。在这篇文章中，我们回顾了目前关于白藜芦醇及其新配方在治疗肺癌中的抗癌作用的证据，并重点讨论了其潜在的机制。

关键词: 白藜芦醇，microRNA，肺癌，细胞凋亡，自噬，氧化应激。

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