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Current Nanomedicine

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ISSN (Print): 2468-1873
ISSN (Online): 2468-1881

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Research Article

Composite and Nanocomposite Thin-film Structures Based on Chitosan Succinamide

Author(s): Renat Salikhov*, Rufina Zilberg, Ilnur Mullagaliev, Timur Salikhov, Yuliya Teres, Elena Bulysheva and Anastasia Ostaltsova

Volume 15, Issue 1, 2025

Published on: 04 December, 2023

Page: [70 - 79] Pages: 10

DOI: 10.2174/0124681873279865231126034248

Price: $65

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Abstract

Aim: Currently, developing composite and nanocomposite materials based on natural polymers is attracting the growing attention of scientists. In particular, chitosan succinamide, a modified biopolymer, has good biocompatibility, biodegradability, and electrical conductivity, allowing it to be used as a functional material for creating various electronic devices, including sensors for use in medicine and pharmaceuticals. Composite sensors based on chitosan derivatives have found application for the recognition and determination of enantiomers of tryptophan, tyrosine, naproxen, and propranolol in human urine and blood plasma in tablet forms of drugs without a preliminary active substance.

Methods: This article discusses the studies on composite and nanocomposite thin-film structures based on chitosan succinamide obtained using various fillers, such as graphene oxide, single-walled carbon nanotubes, and carbon adsorbents.

Result: The studies used cyclic voltammetry, electrochemical impedance spectroscopy, and atomic force microscopy. The results created field-effect transistors based on the films in question as the transport layer.

Conclusion: The mobility of charge carriers was estimated, and the following values were obtained: μ(SCTS) = 0.173cm2/V·s; μ(SCTS-GO) = 0.509 cm2/V·s; μ(SCTS-CP) = 0.269 cm2/V·s; μ(SCTS-CB) = 0.351cm2/V·s; μ(SCTS-SWCNT) = 0.713 cm2/V·s.

Keywords: Thin films, chitosan succinamide, voltammetry, impedance, field-effect transistor, mobility of charge carriers.

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