Title:Direct Oral Anticoagulants use in Patients with Stable Coronary Artery
Disease, Acute Coronary Syndrome or Undergoing Percutaneous Coronary
Intervention
Volume: 29
Issue: 35
Author(s): Marios Sagris*, Panagiotis Theofilis, Angelos Papanikolaou, Alexios S. Antonopoulos, Constantinos Tsioufis and Dimitris Tousoulis
Affiliation:
- 1st Cardiology Department, "Hippokration" General Hospital, University of Athens Medical School, Athens, Greece
Keywords:
Direct oral anticoagulant, coronary artery disease, acute coronary syndrome, percutaneous coronary intervention, coronary artery bypass graft, surgery, dual antiplatelet therapy.
Abstract: The investigation for the optimal anticoagulation strategy for patients with stable coronary artery
disease, acute coronary syndromes, and undergoing percutaneous coronary intervention constitutes a great
challenge for physicians and is a field of extensive research. Although aspirin is commonly recommended as a
protective measure for all patients with coronary artery disease and dual antiplatelet therapy for those undergoing
procedures, such as percutaneous coronary intervention or coronary artery bypass graft surgery, the risk of
recurrent cardiovascular events remains significant. In this context, the shortcomings associated with the use
of vitamin K antagonists have led to the assessment of direct oral anticoagulants as promising alternatives.
This review will explore and provide a comprehensive analysis of the existing data regarding the use of direct
oral anticoagulants in patients with stable coronary artery disease or acute coronary syndrome, as well as their
effectiveness in those undergoing percutaneous coronary intervention or coronary artery bypass graft surgery.
