Unlocking the Benefits of Fasting: A Review of its Impact on Various
Biological Systems and Human Health

Rawan      Mackieh; Nadia      Al-Bakkar; Milena      Kfoury; Nathalie      Okdeh; Hervé      Pietra; Rabih      Roufayel; Christian      Legros; Ziad      Fajloun; Jean-Marc      Sabatier
doi:10.2174/0109298673275492231121062033
Abstract

Fasting has gained significant attention in recent years for its potential health benefits in various body systems. This review aims to comprehensively examine the effects of fasting on human health, specifically focusing on its impact on different body’s physiological systems. The cardiovascular system plays a vital role in maintaining overall health, and fasting has shown promising effects in improving cardiovascular health markers such as blood pressure, cholesterol levels, and triglyceride levels. Additionally, fasting has been suggested to enhance insulin sensitivity, promote weight loss, and improve metabolic health, thus offering potential benefits to individuals with diabetes and metabolic disorders. Furthermore, fasting can boost immune function, reduce inflammation, enhance autophagy, and support the body's defense against infections, cancer, and autoimmune diseases. Fasting has also demonstrated a positive effect on the brain and nervous system. It has been associated with neuroprotective properties, improving cognitive function, and reducing the risk of neurodegenerative diseases, besides the ability of increasing the lifespan. Hence, understanding the potential advantages of fasting can provide valuable insights for individuals and healthcare professionals alike in promoting health and wellbeing. The data presented here may have significant implications for the development of therapeutic approaches and interventions using fasting as a potential preventive and therapeutic strategy.
Keywords: Fasting, cardiovascular system, renin-angiotensin system, immune system, cancer, autophagy, diabetes, nervous system, obesity, COVID-19.
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DOI https://dx.doi.org/10.2174/0109298673275492231121062033	Print ISSN 0929-8673
Publisher Name Bentham Science Publisher	Online ISSN 1875-533X
Current Medicinal Chemistry

Unlocking the Benefits of Fasting: A Review of its Impact on Various Biological Systems and Human Health

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Current Medicinal Chemistry

Unlocking the Benefits of Fasting: A Review of its Impact on Various Biological Systems and Human Health

Abstract

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