Title:Biomarkers for Diagnosing and Treating Fetal Growth Restriction
Volume: 31
Issue: 28
关键词:
生物标志物,胎儿生长限制,预测,药理机制,胎盘,妊娠并发症。
摘要: Fetal growth restriction (FGR), a common obstetric complication, significantly
increases the risks of fetal intrauterine death and neonatal death, and fetuses with
growth restriction are prone to cognitive retardation and various diseases in adulthood.
The early determination of FGR risk is contentious in clinical research, and few indicators
are available for the early prediction and diagnosis of FGR. This review focuses on
the prediction and diagnosis of FGR, as well as the significance of biomarkers for FGR,
such as those related to gene regulation, apoptosis, mitochondrial function, and inflammation.
Although many of these biomarkers are still in the early stages of research, they
are good predictors of the threats to fetal health and safety, and they provide new insights
for the treatment of FGR.