Title:Diabetic Pneumopathy- A Novel Diabetes-associated Complication:
Pathophysiology, the Underlying Mechanism and Combination Medication
Volume: 24
Issue: 9
Author(s): Jyotsana Dwivedi*, Pranay Wal, Biswajit Dash, Mohammad Ovais, Pranjal Sachan and Vaibhav Verma
Affiliation:
- PSIT- Pranveer Singh Institute of Technology (Pharmacy), Kanpur, India
Keywords:
Diabetes, diabetes pneumopathy, pathophysiology, lung diseases, lung infection, pulmonary fibrosis.
Abstract:
Background: The "diabetic lung" has been identified as a possible target organ in
diabetes, with abnormalities in ventilation control, bronchomotor tone, lung volume, pulmonary
diffusing capacity, and neuroadrenergic bronchial innervation.
Objective: This review summarizes studies related to diabetic pneumopathy, pathophysiology
and a number of pulmonary disorders including type 1 and type 2 diabetes.
Methods: Electronic searches were conducted on databases such as Pub Med, Wiley Online
Library (WOL), Scopus, Elsevier, ScienceDirect, and Google Scholar using standard keywords
“diabetes,” “diabetes Pneumopathy,” “Pathophysiology,” “Lung diseases,” “lung infection” for
review articles published between 1978 to 2023 very few previous review articles based their
focus on diabetic pneumopathy and its pathophysiology.
Results: Globally, the incidence of diabetes mellitus has been rising. It is a chronic, progressive
metabolic disease. The "diabetic lung" may serve as a model of accelerated ageing since diabetics'
rate of respiratory function deterioration is two to three-times higher than that of normal,
non-smoking people.
Conclusion: Diabetes-induced pulmonary dysfunction has not gained the attention it deserves
due to a lack of proven causality and changes in cellular properties. The mechanism underlying
a particular lung illness can still only be partially activated by diabetes but there is evidence that
hyperglycemia is linked to pulmonary fibrosis in diabetic people.