Title:A Case Presenting with Neck Pain and High Sedimentation Rate: Amyloid
Goiter
Volume: 24
Issue: 9
Author(s): Puren Gokbulut*, Gonul Koc, Sevdenur Firat, Pelin Oztekin, Pinar Celepli, Seher Kökceoglu and Cavit Culha
Affiliation:
- Department of Endocrinology and Metabolism, Ankara Training and Research Hospital, Ankara, Turkey
Keywords:
Neck Pain, amyloid goiter, familial mediterranean fever, thyroid enlargement, anaplastic thyroid cancer, amyloid accumulations.
Abstract:
Introduction: Amyloid goiter is a rare disease characterized by amyloid deposits that
cause sudden growth in the thyroid gland.
Case Presentation: Here we present a case of a 26-year-old woman with euthyroid amyloid goiter
who presented with subacute granulomatous thyroiditis clinic. Amyloid goiter was detected as
a result of core biopsy from the thyroid parenchyma of the patient with sudden thyroid enlargement.
Surgery was not applied to the patient who had no pressure symptoms or signs. In systemic
amyloidosis secondary to Familial Mediterranean fever, heart and kidney involvement, as well as
the thyroid gland, were detected.
Conclusion: Amyloid accumulation should be considered in addition to anaplastic thyroid cancer
and lymphoma in patients with sudden thyroid enlargement. It should not be overlooked that amyloid
goiter may mimic subacute thyroiditis clinic. Systemic amyloidosis should be considered in
patients with amyloid goiter, and an examination should be made to assess the presence of amyloid
accumulations in other organs.
