Title:Direct-acting Antivirals for Hepatitis C and Implication for Community Pharmacy
Practice
Volume: 29
Issue: 25
Author(s): Sara McEntee, Yifei Liu*, Tahar Mahmoudi, Kathryn Oliver and Chad Cadwell
Affiliation:
- Division of Pharmacy Practice and Administration, University
of Missouri - Kansas City School of Pharmacy, Kansas City, MO, USA
Keywords:
Hepatitis C, direct-acting antivirals, disease state management, community pharmacy, liver disease, direct-acting antivirals.
Abstract: The treatment options for hepatitis C have undergone noteworthy advancements since direct-acting
antivirals (DAAs) were introduced. The selection of a DAA therapy depends on the patient’s genotype, treatment
history, concomitant comorbidities, and concurrent medications. Pharmacists have a pivotal role in
providing clarification and recommendations in selecting appropriate, individualized DAAs for patients. This
commentary aims to (1) provide an overview of DAAs on the market for hepatitis C, and (2) describe the implication
for the care of patients with hepatitis C in a community pharmacy. Community pharmacists can establish
a workflow to recommend appropriate DAA therapy, identify drug interactions, and improve medication adherence
and compliance with lab appointments.