Title:Prevalence and Co-prevalence of Comorbidities among Patients with Type
2 Diabetes Mellitus in the MENA Region: A Systematic Review
Volume: 20
Issue: 7
Author(s): Samir Assaad Khalil*, Sami Azar, Khadija Hafidh, George Ayad and Mohamed Safwat
Affiliation:
- Department of Internal Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt
Keywords:
Diabetes mellitus, type 2 diabetes, prevalence, comorbidities, complications, MENA region.
Abstract:
Aim: The management of type 2 diabetes mellitus is affected by the presence of comorbidities.
This meta-analysis aimed to determine how likely it is for individuals with type 2 diabetes
in the Middle East and North Africa (MENA) region to be living with additional chronic health
conditions.
Methods: We searched for studies published from January 2010 to December 2020 in the PubMed,
Ovid MEDLINE®, Cochrane CENTRAL, Scopus, and Web of Science databases. Studies of
adults with type 2 diabetes in the MENA region were included. We performed a random-effects
meta-analysis of single proportions to calculate each comorbidity's overall prevalence/coprevalence.
Results: Statistically significant co-prevalence was detected at p < 0.01 for angina (pooled proportion:
0.24, 95% CI: 0.06, 0.49), cerebrovascular accident (pooled proportion: 0.16, 95% CI: 0.08,
0.26), coronary artery disease (pooled proportion: 0.25, 95% CI: 0.16, 0.35), coronary heart disease
(pooled proportion: 0.05, 95% CI: 0.01, 0.12), peripheral vascular disease (pooled proportion: 0.19,
95% CI: 0.13, 0.26), hypertension (pooled proportion: 0.56, 95% CI: 0.43, 0.69), renal impairment
(pooled proportion: 0.19, 95% CI: 0.10, 0.29), in addition to hyperlipidemia and overweight/
obesity.
Conclusion: There is evidence of co-prevalence of several comorbidities in patients with type 2
diabetes, highlighting the importance of enhancing communication among healthcare professionals
to develop the optimal management plan for each patient.
