Title:A Review on Nanosponges: An Idiosyncratic Approach for Delivery of
Proactive Molecules
Volume: 9
Issue: 3
Author(s): Meenakshi Attri, Asha Raghav, Komal Rao, Parijat Pandey and Neha Minocha*
Affiliation:
- Amity Institute
of Pharmacy, Amity University, Gurgaon-122412, Haryana, India
Keywords:
Nanosponges, cyclodextrin, target drug delivery, nanotechnology, nanocavity, bioavailability.
Abstract:
Background: A lot of work has been done by many researchers to develop a system that is
targeted at a specific site. Nanosponges are one of the systems that serve this purpose and have several
advantages over other methods.
Objective: The article’s strategy is to provide access to data regarding the nanosponges system, including
its preparation, evaluation, and advantages in various fields, such as the transportation of proteins,
vaccines, biocatalysts, and drugs with enhanced bioavailability. Nanosponges also contribute
significantly to the treatment of breast cancer, lung cancer, fungal infection, water treatment, and topical
application than other approaches.
Method: Nanosponges contain a solid, porous system in which hydrophilic or lipophilic drugs are
loaded at their core in the nanocavity. All the information provided in this article was collected after
analysing various reports on nanosponges available on Google Scholar, PubMed, Scopus, Web of Science,
and Science Direct. It is concluded that the nanosponges have excellent aqueous solubility properties.
Therefore, they can be used as carriers for drugs with poor water solubility. Moreover, greater
bioavailability can be achieved by using the nanosponge approach.
Conclusion: Nanosponges possess various outstanding properties that form the unique system of this
approach. Nanosponges provide an effective carrier system for enzymes, proteins, vaccines, and therapeutic
fields. This review provides a broad overview of the development of nanosponges, their evaluation,
and the uses of nanosponges based on cyclodextrin for drug delivery.
