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Current Drug Research Reviews

Editor-in-Chief

ISSN (Print): 2589-9775
ISSN (Online): 2589-9783

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Letter to the Editor

Biological Potential of Bioactive Bibenzyl Compound Chrysotoxine from the Genus Dendrobium in Medicine

Author(s): Dinesh Kumar Patel*

Volume 16, Issue 3, 2024

Published on: 31 July, 2023

Page: [249 - 250] Pages: 2

DOI: 10.2174/2589977515666230721143129

Open Access Journals Promotions 2
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[1]
Patel K, Patel DK. Secoiridoid amarogentin from ‘gentianaceae’ with their health promotion, disease prevention and modern analytical aspects. Curr Bioact Compd 2020; 16(3): 191-200.
[http://dx.doi.org/10.2174/1573407214666181023115355]
[2]
Patel DK, Patel K. Health benefits of avicularin in the medicine against cancerous disorders and other complications: Biological importance, therapeutic benefit and analytical aspects. Curr Cancer Ther Rev 2022; 18(1): 41-50.
[http://dx.doi.org/10.2174/1573394717666210831163322]
[3]
Patel K, Kumar V, Verma A, Rahman M, Patel DK. β-sitosterol: Bioactive compounds in foods, their role in health promotion and disease prevention “A Concise Report of its Phytopharmaceutical Importance”. Curr Tradit Med 2017; 3(3): 168-77.
[http://dx.doi.org/10.2174/2215083803666170615111759]
[4]
Patel DK, Patel K. Biological potential of cirsimaritin against diabetes mellitus: Medicinal importance and therapeutic benefit. Metabolism 2022; 128155053.
[http://dx.doi.org/10.1016/j.metabol.2021.155053]
[5]
Patel K, Patel DK. Therapeutic benefit and biological importance of ginkgetin in the medicine: Medicinal importance, pharmacological activities and analytical aspects. Curr Bioact Compd 2021; 17(9): e190721190770.
[http://dx.doi.org/10.2174/1573407217666210127091221]
[6]
He L, Su Q, Bai L, et al. Recent research progress on natural small molecule bibenzyls and its derivatives in Dendrobium species. Eur J Med Chem 2020; 204112530.
[http://dx.doi.org/10.1016/j.ejmech.2020.112530] [PMID: 32711292]
[7]
Song JX, Shaw PC, Sze CW, et al. Chrysotoxine, a novel bibenzyl compound, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-κB modulation. Neurochem Int 2010; 57(6): 676-89.
[http://dx.doi.org/10.1016/j.neuint.2010.08.007] [PMID: 20708055]
[8]
Jia-Wei S, Ji-Mei L, Ri-Dao C, et al. Study on chemical bibenzyls in Dendrobium gratiosissimum. Zhongguo Zhongyao Zazhi 2020; 45(20): 4929-37.
[PMID: 33350266]
[9]
Chanvorachote P, Kowitdamrong A, Ruanghirun T, Sritularak B, Mungmee C, Likhitwitayawuid K. Anti-metastatic activities of bibenzyls from Dendrobium pulchellum. Nat Prod Commun 2013; 8: 1934578X1300800.
[http://dx.doi.org/10.1177/1934578X1300800127]
[10]
Fan J, Guan L, Kou Z, Feng F, Zhang Y, Liu W. Determination of chrysotoxine in rat plasma by liquid chromatography–tandem mass spectrometry and its application to a rat pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci 2014; 967: 57-62.
[http://dx.doi.org/10.1016/j.jchromb.2014.07.011] [PMID: 25069096]
[11]
Qiu J, Zhang Y, Xie M. Chrysotoxine attenuates sevoflurane-induced neurotoxicity in vitro via regulating PI3K/AKT/GSK pathway. Signa Vitae 2021; 17: 185-91.
[12]
Bhummaphan N, Pongrakhananon V, Sritularak B, Chanvorachote P. Cancer stem cell–suppressing activity of chrysotoxine, a bibenzyl from Dendrobium pulchellum. J Pharmacol Exp Ther 2018; 364(2): 332-46.
[http://dx.doi.org/10.1124/jpet.117.244467] [PMID: 29217540]
[13]
Khoonrit P, Mirdogan A, Dehlinger A, et al. Immune modulatory effect of a novel 4,5-dihydroxy-3,3´,4´-trimethoxybibenzyl from Dendrobium lindleyi. PLoS One 2020; 15(9): e0238509.
[http://dx.doi.org/10.1371/journal.pone.0238509] [PMID: 32870935]
[14]
Song JX, Shaw PC, Wong NS, et al. Chrysotoxine, a novel bibenzyl compound selectively antagonizes MPP+, but not rotenone, neurotoxicity in dopaminergic SH-SY5Y cells. Neurosci Lett 2012; 521(1): 76-81.
[http://dx.doi.org/10.1016/j.neulet.2012.05.063] [PMID: 22659498]

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