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Review Article

胞葬作用和代谢综合征:叙述性回顾

卷 24, 期 6, 2024

发表于: 10 July, 2023

页: [751 - 757] 页: 7

弟呕挨: 10.2174/1566524023666230710120438

价格: $65

摘要

代谢综合征(MetS)以同时存在高血糖、血脂异常、高血压和中心性肥胖为特征，是心血管疾病(cvd)、死亡率和疾病负担的关键危险因素。细胞凋亡在人体内每秒消灭大约一百万个细胞，保持体内平衡并调节生物体的生命周期。在生理状态下，凋亡细胞通过一个多步骤的过程内化到吞噬细胞，称为胞葬作用。对这些凋亡细胞清除的任何损害都会导致与慢性炎症相关的疾病，如肥胖、糖尿病和血脂异常。另一方面，胰岛素抵抗和MetS可干扰胞葬作用过程。由于没有研究调查胞葬作用和MetS之间的关系，我们决定探索胞葬作用的不同步骤，并描述低效的死细胞清除与MetS进展的关系。

关键词: 胞葬作用，代谢综合征，血脂异常，高血糖，肥胖胞葬作用，肥胖。

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