Title:Recent Updates on Transdermal Drug Delivery Approaches for the
Management of Gout and its Clinical Perspective
Volume: 25
Issue: 2
Author(s): Ranjit K. Harwansh*, Soumya Mishra, Rupa Mazumder, Rohitas Deshmukh and Akhlaquer Rahman
Affiliation:
- Institute of Pharmaceutical Research, GLA University, Mathura, 281406, India
Keywords:
Gout, transdermal, drug delivery, nanocarriers, herbal bio-actives, patch.
Abstract: Oral and injectable drug administration have recently been replaced with transdermal
drug delivery (TDD) approaches, which are less intrusive, less likely to be rejected by patients,
and easier to administer. There is still room for improvement in the treatment of gout with the use
of a TDD system. Gout has become a worldwide epidemic and a severe threat to human beings.
Gout treatment can be accomplished in various ways, including orally and intravenously. Several
traditional options are still useless, cumbersome, and potentially dangerous. Hence, gout therapeutic
options are desperately required for more effective and less toxic drug delivery methods. Antigout
medications using TDD could substantially influence obese people in the future, even if most
trials are still in the animal stages. Thus, this review aimed to provide a concise overview of recent
TDD technologies and anti-gout medication delivery methods that improved therapeutic efficacy
and bioavailability. Moreover, clinical updates on investigational drugs have been discussed to
address the potential findings against gout.