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Current Medicinal Chemistry

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ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Novel Pyrimidin-4-yl-3-amino-pyrrolo[3,4-c]pyrazoles as Protein Kinase C Inhibitors for Treating Diseases

Author(s): Surya K. De*

Volume 31, Issue 8, 2024

Published on: 22 June, 2023

Page: [1036 - 1039] Pages: 4

DOI: 10.2174/0929867330666230531164754

Abstract

This patent describes the series of compounds and their pharmaceutically acceptable salts, such as compound K7 (as a representative potent compound). These protein kinase C selective inhibitors are useful for treating diabetes mellitus and its complications, cancer, ischemia, inflammation, central nervous system disorders, cardiovascular disease, Alzheimer's disease, dermatological disease, virus diseases, inflammatory disorders, or diseases in which the liver is a target organ.

Keywords: Protein kinase C, pyrimidine-pyrrolopyrazoles, cancer, Alzheimer's disease, cardiovascular disease, central nervous system disorders, inflammatory.

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