Title:Carbon Nanocomposites-based Electrochemical Sensors and
Biosensors for Biomedical Diagnostics
Volume: 31
Issue: 25
关键词:
碳纳米复合材料,电分析方法,电化学传感器,生物标志物检测,生物医学诊断,CQDs。
摘要: Detection of emergent biomolecules or biomarkers remains crucial for early diagnosis
in advancing healthcare monitoring and biomedicine. The possibility for rapid detection,
real-time monitoring, high sensitivity, low detection limit, good selectivity, and
low cost is central, among other significant issues for advancing point-of-care diagnosis.
Carbon-based nanocomposites have been employed as sensing materials for various biomarkers
due to their high surface-to-volume ratio, high electrical conductivity, chemical
stability, and biocompatibility. The carbon nanomaterials, such as carbon nanotubes (CNTs),
graphene (GR), carbon quantum dots (CQDs), carbon fibres (CFs), and their nanocomposites
have broadly integrated with numerous sensing electrode materials for the detection
of biomarkers under various experimental settings. The present review includes
the recent advances in the development of carbon nanomaterials-based electrochemical
sensors and biosensors for biomedical applications. The preparation, electrode preparation,
effective utilization of carbon-derived nanomaterials, and their sensing performances
towards numerous biomarkers have been highlighted. The state-of-the-merit,
challenges, and prospects for designing carbon nanocomposites-based electrochemical
sensor/biosensor platforms for biomedical diagnostics have also been described.