Title:Evaluation of the Effectiveness of Remdesivir in the Treatment of
COVID-19 Outpatients: A Retrospective Cohort Study
Volume: 18
Issue: 4
Author(s): Seyed Yaser Foroghi Ghomi, Abolfazl Mohammadbeigi, Abbas Ahmadi, Sajjad Ahmadpour, Mansoureh Shakeri, Seyed Hasan Adeli, Jamshid Vafaeimanesh, Reihane Tabaraii, Rasoul Shajari, Mostafa Vahedian and Akram Asghari*
Affiliation:
- Clinical Research Development Center, Qom University of Medical Sciences, Shahid Beheshti Hospital, Qom, Iran
Keywords:
Remdesivir, PCR, respiratory syndrome, novel coronavirus 2019, Mc Nemar's test, respiratory distress.
Abstract:
Background: The outbreak of acute respiratory syndrome with novel coronavirus 2019
(COVID-19) in December 2019 in Wuhan, China, caused a worldwide outbreak of the disease. To
treat the disease, some drugs were identified and introduced that did not show a significant effect on
the recovery of the disease. Due to the need to manage inpatient beds, this study was conducted to
evaluate the effectiveness of Remdesivir in the treatment of outpatients with moderate to severe
COVID-19.
Methods: The present study was a retrospective cohort with a convenience sampling method. It was
conducted by referring to the records of COVID-19 patients who were referred to the respiratory clinic
of Shahid Beheshti Hospital as outpatients in the period from April to August 2021.
Results: This study was conducted on 263 COVID-19 patients with a mean age of 51.16±14.39 years
from 19 and 90 years old. Data were collected through a researcher-made checklist and analyzed using
SPSS 20. Kolmogorov-Smirnov test, paired t-test, and Mc Nemar's test were used to evaluate the data.
The significance level was considered at the level of 0.05.
Conclusion: Findings revealed that no clear correlation was found between hospitalization and death
rate compared to other patients. In our study, the risk factors for severe COVID-19 did not affect the
rate of hospitalization or death of patients.
