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Endocrine, Metabolic & Immune Disorders - Drug Targets

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ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

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Patent News

Novel 2,4- diaminopyrimidine 5-carboxamides as c-Jun N-terminal Kinase Inhibitors for Treating the Liver Fibrotic Disorder

Author(s): Surya K. De*

Volume 23, Issue 8, 2023

Published on: 20 February, 2023

Page: [1118 - 1123] Pages: 6

DOI: 10.2174/1871530323666230220123228

Abstract

Diaminopyrimidine compounds having the following general structure (I), compositions comprising an effective amount of a diaminopyrimidine compound, and methods for treating or preventing fibrotic liver disorders or other diseases associated with the JNK pathway are discussed in this patent study.

Keywords: Diaminopyrimidine, c-Jun N-terminal kinase, fibrotic liver disorder, mitogen-activated protein kinase, steatosis, reactive oxidant species.

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