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Current Topics in Medicinal Chemistry

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A Comprehensive Review on Phytochemistry, Ethnopharmacology, and Pharmacological Properties of Zingiber roseum (Roxb.) Roscoe

Author(s): Sonu Kumar Mahawer, Ravendra Kumar*, Om Prakash, Sushila Arya, Shailja Singh, Mozaniel Santana de Oliveira* and Dharmendra Singh Rawat

Volume 23, Issue 11, 2023

Published on: 24 February, 2023

Page: [931 - 942] Pages: 12

DOI: 10.2174/1568026623666230126143635

Price: $65

Abstract

Medicinal and aromatic plants are known to have a number of biologically active compounds. Since ancient times, such plants have been used in ethnopharmacology. A number of medicines have been developed from plant origin by researchers and researchers continue to be interested in plant-based medicines. Zingiberaceae is a well-known plant family for such types of medicinal and aromatic plants. Zingiber is the third largest genus of this family and Zingiber roseum (Roxb.) Roscoe is a medicinal and aromatic Z. roseum is a rhizomatous perennial herbaceous plant of this genus, popularly known as “Rosy Ginger” and “Jangli Adrak,” utilized in the Siddha arrangement of medication, and its rhizomes have been used to treat injury, cough, asthma, skin illnesses, gastric ulcers, liver diseases, and heartburn in tradition. It also has ethnopharmacological uses, such as the rhizome of Z. roseum is used for digestion, relieving giddiness, and as a stimulant. Apart from this, it has been reported for several pharmacological activities such as antispasmodic, hepatoprotective, antimicrobial, and anticancer activities, etc. Z. roseum is a reservoir of several chemical constituents such as terpenes and terpenoids such as linalool, α-pinene, β-pinene, limonene, terpinen-4-ol, α- terpineol, etc., phenols, flavonoids, alkaloids, saponins, and ascorbic acid along with important unique constituents such as zerumbone which are responsible for its medicinal and other biological activities. In this review article, we discussed the thorough knowledge published by researchers regarding the phytochemistry, ethnopharmacological, and mediational properties of Z. roseum and its botanical descriptions.

Keywords: Natural products, Phytochemistry, Ethnopharmacological, Pharmacological properties, Essential oils, Antispas-modic, Hepatoprotective.

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Graphical Abstract

[1]
Pieters, L.; Vlietinck, A.J. Bioguided isolation of pharmacologically active plant components, still a valuable strategy for the finding of new lead compounds? J. Ethnopharmacol., 2005, 100(1-2), 57-60.
[http://dx.doi.org/10.1016/j.jep.2005.05.029] [PMID: 15996842]
[2]
Balunas, M.J.; Kinghorn, A.D. Drug discovery from medicinal plants. Life Sci., 2005, 78(5), 431-441.
[http://dx.doi.org/10.1016/j.lfs.2005.09.012] [PMID: 16198377]
[3]
Theilade, I. A synopsis of the genus Zingiber (Zingiberaceae) in Thailand. Nord. J. Bot., 1999, 19(4), 389-410.
[http://dx.doi.org/10.1111/j.1756-1051.1999.tb01220.x]
[4]
Sabu, M. Zingiberaceae and Costaceae of South India; Indian Association for Angiosperm Taxonomy, 2006, pp. 264-277.
[5]
Flowers of India. Available from: http://www.flowersofindia.net/catalog/slides/Rosy%20Ginger.html
[6]
Mittal, D.K.; Jena, A.K.; Joshi, D. Ameliorative effects of Polygonum bistorta and Zingiber roseum on carbon tetrachloride treated rats. World J. Pharm. Pharm. Sci., 2013, 2, 3522-3531.
[7]
Maheshwari, J.K.; Kalakoti, B.S.; Lal, B. Ethnomedicine of bhil tribe of Jhabua district, m. P. Anc. Sci. Life, 1986, 5(4), 255-261.
[PMID: 22557535 ]
[8]
Babu, N.C.; Naidu, M.T.; Venkaiah, M. Ethnomedicinal plants of Kotia hills of Vizianagaram district, Andhra Pradesh, India. J. Phytol., 2010, 2(6), 76-82.
[9]
Prakash, O.; Kasana, V.K.; Pant, A.K.; Zafar, A.; Hore, S.K.; Mathela, C.S. Phytochemical composition of essential oil from seeds of Zingiber roseum Rosc. and its antispasmodic activity in rat duodenum. J. Ethnopharmacol., 2006, 106(3), 344-347.
[http://dx.doi.org/10.1016/j.jep.2006.01.016] [PMID: 16510259]
[10]
Ganesan, S.; Pandi, N.R.; Banumathy, N. Ethnomedicinal survey of Alagarkoil hills (reserved forest), Tamil nadu, India. EJ. Indiana Med., 2007, 1(1), 1-18.
[11]
Padal, S.B.; Ramakrishna, H.; Devender, R. Ethnomedicinal studies for endemic diseases by the tribes of Munchingiputtu Mandal, Visakhapatnam district, Andhra Pradesh, India. Int. J. Med. Aromat. Plants, 2012, 2(3), 453-459.
[12]
Al-Amin, M.; Siddiqui, M.A.; Ruma, S.A.; Eltayeb, N.M.; Sultana, G.N.N. Antimicrobial activity of the crude extract, fractions and isolation of zerumbone from the rhizomes of Zingiber roseum. J. Res. Pharm., 2019, 23(3), 559-566.
[http://dx.doi.org/10.12991/jrp.2019.163]
[13]
Puupponen-Pimiä, R.; Nohynek, L.; Meier, C.; Kähkönen, M.; Heinonen, M.; Hopia, A.; Oksman-Caldentey, K.M. Antimicrobial properties of phenolic compounds from berries. J. Appl. Microbiol., 2001, 90(4), 494-507.
[http://dx.doi.org/10.1046/j.1365-2672.2001.01271.x] [PMID: 11309059]
[14]
Jeevan Ram, A.; Bhakshu, L.M.; Venkata Raju, R.R. In vitro antimicrobial activity of certain medicinal plants from Eastern Ghats, India, used for skin diseases. J. Ethnopharmacol., 2004, 90(2-3), 353-357.
[http://dx.doi.org/10.1016/j.jep.2003.10.013] [PMID: 15013201]
[15]
Kress, W.J.; Liu, A.Z.; Newman, M.; Li, Q.J. The molecular phylogeny of Alpinia (Zingiberaceae): a complex and polyphyletic genus of gingers. Am. J. Bot., 2005, 92(1), 167-178.
[http://dx.doi.org/10.3732/ajb.92.1.167] [PMID: 21652395]
[16]
Christine, S. Clonal propagation of Curcuma zedoaria rocs and Zingiber zerumbet, Ph D thesis, University Sains Malaysia, 2007.
[17]
Pancharoen, O.; Prawat, U.; Tuntiwachwuttikul, P. Phytochemistry of the zingiberaceae. Stud. Nat. Prod. Chem., 2000, 23, 797-865.
[http://dx.doi.org/10.1016/S1572-5995(00)80142-8]
[18]
Sharifi-Rad, M.; Varoni, E.; Salehi, B.; Sharifi-Rad, J.; Matthews, K.; Ayatollahi, S.; Kobarfard, F.; Ibrahim, S.; Mnayer, D.; Zakaria, Z.; Sharifi-Rad, M.; Yousaf, Z.; Iriti, M.; Basile, A.; Rigano, D. Plants of the genus Zingiber as a source of bioactive phytochemicals: From tradition to pharmacy. Molecules, 2017, 22(12), 2145.
[http://dx.doi.org/10.3390/molecules22122145] [PMID: 29207520]
[19]
CoL. Catalogue of Life. 2021. Available from: https://www.catalogueoflife.org
[20]
Pandey, S.; Prakash, O.; Zafar, A.; Hore, S.K.; Pant, A.K.; Mathela, C.S. Myorelaxant effect of essential oil of rhizome of Alpinia calcarata Rosc. on rat duodenal smooth muscle. Nat. Prod. Commun., 2007, 2(7), 1934578X0700200718.
[21]
Prakash, O.; Joshi, S.; Pant, A.K.; Chanotiya, C.S.; Mathela, C.S. Volatile constituents of rhizomes and leaves of Alpinia allughas Roscoe. J. Essent. Oil Res., 2007, 19(5), 407-409.
[http://dx.doi.org/10.1080/10412905.2007.9699937]
[22]
Kumar, R.; Sethi, S.; Prakash, O.; Pant, A.K.; Kumar, M.; Isidorov, V.A.; Szczepaniak, L. Chemical composition of rhizome oleoresin and anti-inflammatory, antinociceptive and antipyretic activity of oleoresins of Alpinia allughas Roscoe. from tarai region of Uttarakhand. Indones. J. Pharm., 2017, 28(3), 136.
[http://dx.doi.org/10.14499/indonesianjpharm28iss3pp136]
[23]
Joshi, S.; Prakash, O.; Pant, A.K.; Mathela, C.S. Chemical composition, and antioxidant and antimicrobial activities of Alpinia nutans Rosc. J. Essent. Oil Res., 2010, 22(1), 85-90.
[http://dx.doi.org/10.1080/10412905.2010.9700270]
[24]
Sethi, S.O.; Prakash, O.; Pant, A.K.; Batra, M.U.; Kumar, M.A. Hepatoprotective and antioxidant activity of Alpinia malaccensis Roscoe rhizome. Int. J. Pharm. Pharm. Sci., 2015, 7, 220-224.
[25]
Sethi, S.; Prakash, O.; Pant, A.K. Antioxidant potential and total phenolic content of essential oil and various extracts from Alpinia malaccensis (Burm. f.). Roscoe. Asian J. Chem., 2015, 27(11), 4085-4088.
[http://dx.doi.org/10.14233/ajchem.2015.19097]
[26]
Sonali, S.; Prakash, O.M.; Pant, A.K. Antifungal activity of essential oil of leaves of Alpinia malaccensis (Burm. f.). Roscoe. Int. J. Basic Appl. Agric. Res., 2015, 13(2), 58-60.
[27]
Sethi, S.; Prakash, O.; Pant, A.K. Phytochemical analysis, antioxidant assay and antifungal activity of essential oil and various extracts of Alpinia malaccensis (Burm.f.) Roscoe leaves. Cogent Chem., 2016, 2(1)1223781
[http://dx.doi.org/10.1080/23312009.2016.1223781]
[28]
Sethi, S.; Prakash, O.; Pant, A.K.; Kumar, M. Phytochemical analysis and pharmacological activities of methanolic extract and essential oil from rhizomes of Alpinia malaccensis (Burm. f.) Roscoe. J. Essent. Oil-Bear. Plants, 2017, 20(4), 1018-1029.
[http://dx.doi.org/10.1080/0972060X.2017.1374216]
[29]
Tamta, A.; Prakash, O.; Punetha, H.; Pant, A.K. Chemical composition and in vitro antioxidant potential of essential oil and rhizome extracts of Curcuma amada Roxb. Cogent Chem., 2016, 2(1)1168067
[http://dx.doi.org/10.1080/23312009.2016.1168067]
[30]
Arya, N.; Prakash, O.; Tripathi, S. Vivekanand; Pant, A.K. Curcuma longa L.: elemental and nutritional profiling of fifty accessions from Uttarakhand region in India. Asian J. Chem., 2015, 27(11), 4160-4166.
[http://dx.doi.org/10.14233/ajchem.2015.19195]
[31]
Arya, N.; Prakash, O.; Kumar, S. Vivekanand; Pant, A.K. Curcumin profiling and genetic diversity of different accessions of Curcuma longa L. Asian Pac. J. Trop. Dis., 2016, 6(1), 70-74.
[http://dx.doi.org/10.1016/S2222-1808(15)60987-2]
[32]
Kumar, R.; Prakash, O.; Pant, A.K.; Isidorov, V.A.; Mathela, C.S. Chemical composition, antioxidant and myorelaxant activity of essential oils of Globba sessiliflora Sims. J. Essent. Oil Res., 2012, 24(4), 385-391.
[http://dx.doi.org/10.1080/10412905.2012.692915]
[33]
Kumar, R.; Om, P.; Anil, K.P.; Mahesh, K.; Valary, A.I.; Lech, S. Chemical composition and anti-inflamatory, anti-nociceptive and antipyretic activity of rhizome essential oil of Globba sessiliflora Sims. collected from Garhwal region of Uttarakhand. J. Herb. Drugs, 2017, 8(1), 59-69.
[http://dx.doi.org/10.18869/JHD.2017.59]
[34]
Bathla, R.; Sethi, S.; Prakash, O.; Punetha, H.; Pant, A.K.; Batra, M.; Kumar, M. Phytochemical analysis, antioxidant and hepatoprotective activity of Roscoea purpurea, a Zingiberaceous herb collected from Kumaun hills of Uttarakhand. Asian J. Tradit. Med., 2016, 11(6), 141-152.
[35]
Prakash, O.; Pant, A.K.; Mathela, C.S. Linalool-Rich Essential Oil from the Rhizomes of Zingiber roseum Rosc. J. Essent. Oil Res., 2006, 18(6), 638-639.
[http://dx.doi.org/10.1080/10412905.2006.9699190]
[36]
Premram, A.S.; Parki, A.; Chaubey, P.; Prakash, O.; Kumar, R.; Punetha, H.; Pant, A.K. Phytochemical diversity among parts of Zingiber roseum Rosc. extracts with their antioxidant and antifungal activity. J. Biol. Active Prod. Nat., 2018, 8(4), 255-264.
[http://dx.doi.org/10.1080/22311866.2018.1499439]
[37]
Prakash, O.; Zafar, A.; Hore, S.K.; Pant, A.K.; Mathela, C.S. Effect of aqueous extracts of Hedychium coronarium Koen. rhizomes and seeds and rhizomes of Zingiber roseum Rosc. on rat duodenal smooth muscle. Vet. J. Pharmacol. Toxic., 2005, 4(1-2), 50-51.
[38]
Pal, J.; Singh, S.P.; Prakash, O.; Batra, M.; Pant, A.K.; Mathela, C.S. Hepatoprotective and antioxidant activity of Zingiber chrysanthum Rosec. rhizomes. Asian J. Tradit. Med., 2011, 6(6), 242-251.
[39]
Chandra, D.; Chaubey, P.; Parki, A.; Prakash, O.; Kumar, R.; Pant, A.K. Study on chemical diversity among plant parts of Zingiber chrysanthum and their antioxidant assay. J. Biol. Active Prod. Nat., 2017, 7(2), 107-117.
[http://dx.doi.org/10.1080/22311866.2017.1326318]
[40]
Palariya, D. Dhami, A.; Singh, A.; Kumar, R.; Chandra, D.; Pant, A.K.; Prakash, O.; Rawat, D.S. β-Pinene rich seed essential oil of Zingiber chrysanthum Roscoe (Zingiberaceae) from Kumaun Lesser Himalaya, Uttarakhand and its biological activities. J. Essent. Oil-Bear. Plants, 2019, 22(5), 1349-1361.
[http://dx.doi.org/10.1080/0972060X.2019.1700828]
[41]
Arora, M.; Punetha, H.; Prakash, O.; Gaur, A.K.; Pant, A.K. Optimization of in vitro regeneration schedule of Zingiber Chrysanthum Rosc. plantlets from rhizome bud explants. Int. j. environ. agric. Biotech., 2012, 5(2), 83-88.
[42]
Prakash, O.; Rajput, M.; Kumar, M.; Pant, A.K. Kumar.; Pant, A.K. Chemical composition and antibacterial activity of rhizome oils from Hedychium coronarium Koenig and Hedychium spicatum Buch-Ham. J. Essent. Oil-Bear. Plants, 2010, 13(2), 250-259.
[http://dx.doi.org/10.1080/0972060X.2010.10643819]
[43]
Rawat, A.; Thapa, P.; Prakash, O.; Kumar, R.; Pant, A.K.; Srivastava, R.M.; Rawat, D.S. Chemical composition, herbicidal, antifeedant and cytotoxic activity of Hedychium spicatum Sm.: A Zingiberaceae herb. Trends Phytochem. Res., 2019, 3(2), 123-136.
[44]
Rawat, A.; Prakash, O.; Kumar, R.; Arya, S.; Srivastava, R.M. Hedychium spicatum Sm.: Chemical composition with biological activities of methanolic and ethylacetate oleoresins from rhizomes. J. Biol. Active Prod. Nat., 2021, 11(3), 269-288.
[http://dx.doi.org/10.1080/22311866.2021.1923572]
[45]
Pant, A.K.; Mathela, C.S.; Dev, V.; Bottini, A.T. Rhizome essential oil of Hedychium aurantiacum (Zingiberaceae), a potential source of (+)-linalool. J. Essent. Oil Res., 1992, 4(2), 129-131.
[http://dx.doi.org/10.1080/10412905.1992.9698033]
[46]
Joshi, S.; Chanotiya, C.S.; Agarwal, G.; Prakash, O.; Pant, A.K.; Mathela, C.S. Terpenoid compositions, and antioxidant and antimicrobial properties of the rhizome essential oils of different Hedychium species. Chem. Biodivers., 2008, 5(2), 299-309.
[http://dx.doi.org/10.1002/cbdv.200890027] [PMID: 18293443]
[47]
Kumar, R.; Prakash, O.; Singh, S.P.; Pant, A.K.; Isidorov, V.A.; Szczepaniak, L. Chemical composition, antioxidant and myorelaxant activity of essential oil of Hedychium aurantiacum. Asian J. Chem., 2017, 29(12), 2587-2591.
[http://dx.doi.org/10.14233/ajchem.2017.20701]
[48]
Babu, C.R. Herbaceous Flora of Dehradun; Publication and Information Directorate; CSIR: New Delhi, 1977, pp. 104-105.
[49]
Sasidharan, N. Zingiber roseum (Roxb.) Roscoe. India Biodiversity Portal, Species Page: Zingiber roseum (Roxb.) Roscoe., Available from: https://indiabiodiversity.org/species/show/264132
[50]
Secretariat, G.B.I.F. Zingiber roseum (Roxb.) Roscoe. GBIF Backbone Taxonomy. Checklist dataset 2021.
[http://dx.doi.org/10.15468/39omei]
[51]
Sundaram, S.S.; Suresh, K.; Sundaram, S.P. Indigenous knowledge on medicinal plants used to treat various human ailments in Madurai District, Tamil Nadu, India. J. Med. Plants Res., 2019, 7(3), 117-123.
[52]
Mawla, F.; Khatoon, S.; Rehana, F.; Jahan, S.; Shelley, M.M.; Hossain, S.; Haq, W.M.; Rahman, S.; Debnath, K.; Rahmatullah, M. Ethnomedicinal plants of folk medicinal practitioners in four villages of Natore and Rajshahi districts, Bangladesh. Am. Eur. J. Sustain. Agric., 2012, 6, 406-416.
[53]
Pattanaik, C.; Reddy, C.S.; Reddy, K.N. Ethno-medicinal survey of threatened plants in Eastern Ghats, India. Our Nat., 1970, 7(1), 122-128.
[http://dx.doi.org/10.3126/on.v7i1.2559]
[54]
Joseph, J.M.; Thomas, B.; Rajendran, A.; Prabhu Kumar, K.M. Medicinal Chasmophytes of Urumbikkara Hills, Idukki district, Kerala, India. Asian J. Pharm. Sci. Techno., 2015, 5(1), 11-17.
[55]
Saxena, H.O. Observations on the ethnobotany of Madhya Pradesh. Nelumbo, 1986, 28(1-4), 149-156.
[56]
Pragadheesh, V.S.; Yadav, A.; Singh, M.; Chanotiya, C.S. Characterization of volatile components of Zingiber roseum essential oil using capillary GC on modified cyclodextrins. Nat. Prod. Commun., 2013, 8(2), 1934578X1300800223.
[57]
Chanotiya, C.S.; Yadav, A. Enantiomeric composition of (3 R)-(-)- and (3 S)-(+)-linalool in various essential oils of Indian origin by enantioselective capillary gas chromatography-flame ionization and mass spectrometry detection methods. Nat. Prod. Commun., 2009, 4(4), 1934578X0900400424.
[58]
Panda, D.; Behera, A.K.; Padhan, B.; Nayak, J.K. Chemical profiling of selected plants of Zingiberaceae used in ethnomedicine of Koraput, India. J. Stress Physiol. Biochem., 2020, 16(1), 50-60.
[59]
Nayak, S.; Jena, A.K.; Mittal, D.K.; Joshi, D. GC–MS analysis of phytoconstituents of some wild Zingiberaceae plants methanolic rhizome extracts. Res. Plant Sci., 2014, 2(1), 1-5.
[60]
Amanat, M.; Reza, M.S.; Shuvo, M.S.R.; Ahmed, K.S.; Hossain, H.; Tawhid, M.; Saifuzzaman, M.; Islam, M.S.; Mazumder, T.; Islam, M.A.; Daula, A.F.M.S.U. Zingiber roseum Rosc. rhizome: A rich source of hepatoprotective polyphenols. Biomed. Pharmacother., 2021, 139111673
[http://dx.doi.org/10.1016/j.biopha.2021.111673] [PMID: 33965729]
[61]
Pakalapati, S.; Devara, G.; Mamillapalli, A. Antioxidant, antiproliferative and antimicrobial activities study of Zingiber roseum rosc. An endangered medicinal plant. Int. J. Sci. Res., 2013, 2(7), 2277-8179.
[62]
Mittal, D.K.; Jena, A.K.; Joshi, D. Mechanism of Polygonum bistorta and Zingiber roseum against toxicity. J. Drug Metab. Toxicol., 2014, 4(161), 1-3.

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