Title:Facial Palsy Induced by Covaxin in Adolescent Female - A Rare Case Report
Volume: 18
Issue: 4
Author(s): Priyanka Jivrambhai Chaudhari*, Uditkumar Bhupeshkumar Chawda, Bhagirath Jayantilal Bhad, Ashvin Vasantlal Mevada*Sushilkuamar Gopikant Jha
Affiliation:
- Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat 364001, India
- Department of Pharmacology, Government Medical College, Bhavnagar, Gujarat 364001, India
Keywords:
Facial paralysis, COVID-19, SARS-CoV-2, vaccines, adverse event/reaction, adjuvant, immunization.
Abstract:
Background: The world has seen nearly 2 years of a pandemic caused by the SARS-CoV-2
virus, notoriously known as COVID-19. Several vaccines have been approved under Emergency Use
Authorization (EUA) to combat the disease, one of which is Covaxin, an inactivated adjuvant SARSCoV-
2 vaccine that is generally well tolerated and has fewer side effects. However, we recently have
seen a rare case of facial palsy (paralysis) following Covaxin vaccination in an adolescent girl.
Case Presentation: A 16 years old adolescent girl presented with chief complaints of left side deviation
of mouth with difficulty in closing right eye after 29 days of receiving the first dose of Covaxin,
which was finally diagnosed as a "Covaxin induced facial palsy". Her symptoms were alleviated
with some supportive measures, steroid and antiviral treatment, with full recovery.
Conclusion: The case depicts facial nerve paralysis following Covaxin use, possibly the first of its
kind. This case illustrates plausible explanation to Covaxin use and occurrence of facial palsy,
however, further studies required to establish causal relationship.
