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Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Research Article

Deep Learning Models for Coronary Atherosclerosis Detection in Coronary CT Angiography

Author(s): Amel Laidi*, Mohammed Ammar*, Mostafa El Habib Daho and Said Mahmoudi

Volume 20, 2024

Published on: 17 January, 2023

Article ID: e211222212072 Pages: 9

DOI: 10.2174/1573405619666221221092933

open_access

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Abstract

Background: Patients with atherosclerosis have a rather high risk of showing complications, if not diagnosed quickly and efficiently.

Objective: In this paper we aim to test and compare different pre-trained deep learning models, to find the best model for atherosclerosis detection in coronary CT angiography.

Methods: We experimented with different pre-trained deep learning models and fine-tuned each model to achieve the best classification accuracy. We then used the Haar wavelet decomposition to improve the model’s sensitivity.

Results: We found that the Resnet101 architecture had the best performance with an accuracy of 95.2%, 60.8% sensitivity, and 90.48% PPV. Compared to the state of the art which uses a 3D CNN and achieved 90.9% accuracy, 68.9% Sensitivity and 58.8% PPV, sensitivity was quite low. To improve the sensitivity, we chose to use the Haar wavelet decomposition and trained the CNN model with the module of the three details: Low_High, High_Low, and High_High. The best sensitivity reached 80% with the CNN_KNN classifier.

Conclusion: It is possible to perform atherosclerosis detection straight from CCTA images using a pretrained Resnet101, which has good accuracy and PPV. The low sensitivity can be improved using Haar wavelet decomposition and CNN-KNN classifier.

Keywords: Deep learning, Atherosclerosis, Coronary artery diseases, Wavelet decomposition, Angiography, Resnet101.


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