Title:Role of Non-coding RNA in the Pathogenesis of Intestinal Ischemia-
Reperfusion Injury
Volume: 30
Issue: 36
关键词:
肠,缺血再灌注损伤,非编码RNA,微RNA,环状RNA,长链非编码RNA。
摘要: Intestinal ischemia-reperfusion injury is a relatively common clinical condition
that seriously threatens the prognosis of patients; however, the exact mechanism of
intestinal ischemia-reperfusion injury has not been clarified. Recent studies have found
that noncoding RNAs, including but not limited to lncRNA, circRNA, and miRNA, play
an important role in the pathogenesis of intestinal ischemia-reperfusion. The findings cited
in this paper reveal the expression, function, and mechanism of noncoding RNAs during
intestinal ischemia-reperfusion. The mechanistic roles of noncoding RNAs in the occurrence
and development of intestinal ischemia-reperfusion are discussed, including cell
proliferation, autophagy, oxidative stress, apoptosis, oxidative stress, iron death, and
many other aspects. However, many unknown mechanisms of association between noncoding
RNAs and intestinal ischemia-reperfusion remain to be investigated.