Title:A Review on the Synthesis and Pharmacological Activity of
Heterocyclic Compounds
Volume: 13
Issue: 1
Author(s): Jyoti Baranwal*, Smriti Kushwaha, Swastika Singh and Archana Jyoti
Affiliation:
- Department of Chemistry, S. S. Khanna Girls’ Degree College, Prayagraj 211001, Uttar Pradesh, India
Keywords:
Bioactivity, biologically active compounds, drugs, heteroatom, heterocycles, pharmacological activity.
Abstract: Biologically active compounds play a very important role in our daily life. Almost
all biologically active compounds contain heteroatoms and among these, a major portion
is heterocycles. Heterocycles are a significant component in drug development programs.
Drugs containing a heterocyclic moiety are highly valued resources in the fight
against human and animal diseases. Some of these compounds are utilized as anticonvulsants
antivirals, anti-inflammatory, and central vasodilators, while others are used as nontherapeutic
anthelmintics, diuretics, anti-hypertensives, uricosurics, fungicides, bactericides,
and herbicides. In this review, we have discussed the chemistry of heterocyclic compounds
such as Quinoxaline, Triazole, Pyrimidine, Pyridine, Oxadiazole, Thiazole, Indole,
and Azepine. Besides some of their recent synthetic methodologies, their pharmaceutical
importance is also discussed. Undoubtedly, the contents of this review will motivate readers
to do more novel work in this area which will accelerate the journey toward the exploration
of the pharmacological activity of heterocyclic compounds.
