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Mini-Review Article

Elabela肽:治疗学的一个新兴靶点

卷 23, 期 14, 2022

发表于: 15 September, 2022

页: [1304 - 1318] 页: 15

弟呕挨: 10.2174/1389450123666220826160123

价格: $65

摘要

Elabela是一种具有生物活性的微肽，被认为是Apelin受体的第二个内源性配体，广泛分布于不同的组织和器官中。Elabela在血压控制、心脏形态发生、细胞凋亡、血管生成、细胞增殖、迁移等多种生理过程中发挥着重要作用。Elabela也与病理状况有关，如心脏功能障碍、心力衰竭、高血压、肾病、癌症和中枢神经系统疾病。Elabela与这些疾病的联系使它成为他们治疗的潜在目标。本文综述了Elabela肽的生理作用及其在各种疾病中的意义。

关键词: Elabela，APJ受体，心血管疾病, 肾脏疾病, 癌症, 中枢神经系统疾病。

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图形摘要

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