Title:A Case of Intracranial Space-occupying Lesion Caused by Infection of
AIDS-associated Talaromyces Marnefei
Volume: 19
Author(s): Shuyi Xie, Lieguang Zhang, Deyang Huang, Yanhong Yang, Zhiping Zhang, Yanhua Xiao, Xiaoping Tang*Jinxin Liu*
Affiliation:
- Department of Radiology, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, No. 8, Huaying Road, Baiyun District, Guangzhou 510060, Guangdong Province, China
- Department of Radiology, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, No. 8, Huaying
Road, Baiyun District, Guangzhou 510060, Guangdong Province, China
Keywords:
Talaromyces marneffei, intracranial infection, magnetic resonance imaging, fungus, lobe, mass.
Abstract:
Background: Talaromyces marneffei (T. marneffei) is a heat-dimorphic fungus that commonly
causes fatal opportunistic infections in immunocompromised patients, such as those with human
immunodeficiency virus (HIV) infection.
Case Presentation: In this case report we describe a case of intracranial infection of T. marneffei in a
42-year-old AIDS patient. Contrast enhanced MRI showed the left occipital lobe mass with ring enhancement,
MRS showed elevated AAs and Lip waves in the mass. Surgical resection of the occipital
lobe confirmed the lesion to be T. marneffei infection and possibly with tuberculosis after a pathological
examination. Patients with intracranial ring enhancing space-occupying lesions on MRI should be
considered for intracranial T. marneffei infection. Intracranial T. marneffei infection is relatively rarely
reported and recently studied.
Conclusion: The MRI, in this case, suggests that ring enhancement mass and elevated AAs and Lip
waves are helpful in the diagnosis of T. marneffei infection.
